He co-hosted a nightly show with Tom Snyder on the CBS Radio Network during the 1990s. Mark Simone worked for WABC from 1999 to 2012 hosting a Saturday morning talk show and the Saturday Night Show. He joined WOR in 2013 and began hosting the midmorning weekday timeslot. He is also a member of the Board of Directors for the Police Athletic League of New York City which is a charity organization for youth.